The St. Padre Pio Shrine is an outdoor Roman Catholic shrine in the Landisville section of Buena, New Jersey dedicated to the 20th-century Italian saint Padre Pio. The shrine was conceived in 1997 by Marie and Pete D’Andrea, Italian-American farmers in Buena, and was designed by local architect Ron Angelo. The structure was completed in 2002, and consists of a four-story monument and three statues on ten acres of land. The monument is composed of a steel frame covered with white stucco, and inside the monument are the statues of Padre Pio, the Blessed Mother, and the Sacred Heart of Jesus. The shrine has a Glove Relic (which is a part of the glove that St. Padre Pio wore to hide his stigma wounds).

Rosary prayer sessions are held at the shrine on Wednesday evenings at 7:00 PM, and some individuals have claimed to have experienced physical & spiritual healings resulting from praying at the shrine.